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What will a month cost?
What it costs
$189/mo
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7 min
Published
September 2026

Compounded Semaglutide Cost: The Monthly Market, Computed

What compounded semaglutide costs per month by form, against the branded cash price, with the vial, dose and pharmacy questions that move the figure.

ByDerek MossPricing analystPublished

Compounded semaglutide injections typically cost $184 a month. Published prices run from $76 to $485 across 380 sellers.

The table splits the market three ways. The live board is semaglutide prices.

Monthly semaglutide price by supply and form, computed from sellers that publish a monthly figure
ProductSellersLowTypicalHighRead through
Compounded, injection380$76$184$485September 2026
Compounded, oral or sublingual76$99$222$599September 2026
Brand, cash price at a telehealth12$119$286$449.99September 2026
Monthly semaglutide price by supply and form, computed from sellers that publish a monthly figure. Each seller counted once per row, at its lowest monthly price. Promotional and non-monthly figures excluded.

Price at the dose you will stay on

Semaglutide doses step up over months. A seller may quote the starting dose. Ask for the price at each step.

Some charge one flat monthly price across doses. Others raise it as the dose climbs. Compare at the top dose, not the first.

Then add the fees. Membership, consult, labs, supplies and shipping are listed in the peptide therapy cost guide.

The vial sets a hidden limit

Compounded semaglutide often ships in a vial holding several doses[1]. FDA generally recommends using such a vial within 28 days of first use[1].

That matters for price. A vial sized for ten weeks is not ten weeks of drug. FDA says to discard it at 28 days, even if the compounder’s label says longer[1].

Cold shipping matters too. FDA has received complaints of vials arriving warm[1]. It advises not using an injectable GLP-1 that arrives without enough refrigeration[1]. Ask who pays for a replacement.

What compounded means for the buyer

Compounded drugs are not FDA-approved. FDA does not review them for safety, effectiveness or quality before marketing[1].

FDA flags semaglutide salt forms. Semaglutide sodium and semaglutide acetate are different active ingredients from the approved drug[1]. FDA knows of no lawful basis for compounding them[1]. Ask the seller which form it dispenses.

Through May 31, 2026, FDA had 990 adverse-event reports tied to compounded semaglutide[1]. FDA notes these are likely underreported[1].

Where the supply comes from

A secret-shopper study run in 2025 covered 75 clinics and medical spas in two states[3]. Of those, 42 (56.0%) offered compounded GLP-1s mixed with B vitamins[3].

The study traced 23 supplying compounders[3]. Four of 21 checked (19.0%) were not licensed for sterile compounding[3]. Ask the seller to name the pharmacy. The difference between pharmacy tiers is in 503A vs 503B.

The larger outsourcing tier faces its own limit. In May 2026, FDA proposed not to put semaglutide on the 503B bulks list[2]. Without that listing or a shortage, an outsourcing facility cannot compound it from bulk[2].

Before you pay

Four questions settle most of the price.

  • What is the monthly price at each dose step?
  • How many weeks does one vial last, given the 28-day limit?
  • Which pharmacy compounds it, and is it semaglutide base or a salt?
  • What does canceling or pausing cost?

The tirzepatide market follows the same rules. Its figures are in the compounded tirzepatide cost guide. Reviewed sellers are on the reviews page.

FAQ

4 questions

How much does compounded semaglutide cost per month?

This page computes the typical, low and high monthly price for compounded semaglutide injections from sellers that publish one, with oral and branded prices beside it for comparison.

Does the price of compounded semaglutide go up with the dose?

At some sellers it does and at others it is flat. Ask for the price at each dose step and compare sellers at the maintenance dose.

How long does a vial of compounded semaglutide last?

FDA generally recommends discarding a multi-dose vial 28 days after first use, even if medication remains or the label says otherwise.

Is compounded semaglutide FDA-approved?

No. Compounded drugs are not FDA-approved, and FDA does not review them for safety, effectiveness or quality before they are marketed.

Sources

4 cited
  1. [1]U.S. Food and Drug Administration (2026). FDA's Concerns with Unapproved GLP-1 Drugs Used for Weight Loss FDA, Drug Alerts and Statements. Source
  2. [2]Food and Drug Administration (2026). List of Bulk Drug Substances for Which There Is a Clinical Need Under Section 503B of the Federal Food, Drug, and Cosmetic Act (91 FR 23431) Federal Register. Source
  3. [3]DiStefano MJ, Tilley A, Paratane D, et al. (2026). Postshortage Compounded GLP-1 RA Market in 2 States With Potentially High Demand JAMA Health Forum. PMID 42467450
  4. [4]Kopp KL, Lamberth K, Schelde O, et al. (2026). Impurities and Potential Immunogenicity Associated With Follow-on and Compounded Glucagon-like Peptide-1 Receptor Agonists Pharmaceutical Research. PMID 42533250

Where to buy Semaglutide

Lowest injection prices
  1. 1CollectivePriced, not reviewed$76/moGet price →
  2. 2Lean MedsPriced, not reviewed$79/moGet price →
  3. 3RxPepsDirectPriced, not reviewed$79/moGet price →

Medication price as each seller publishes it, before fees. The full Semaglutide price board