A month of prescription NAD+ injections typically costs $191.25. Prescription oral NAD+ typically costs $189. Store-bought supplements are a different product, and are not priced here.
| Form | Sellers | Low | Typical | High |
|---|---|---|---|---|
| Injection | 161 | $60 | $191.25 | $349 |
| Oral | 12 | $100 | $189 | $249 |
| Sublingual | 6 | $169 | $219 | $249 |
| Nasal spray | 77 | $69 | $150 | $299 |
| Topical | 13 | $59 | $95 | $299 |
The NAD+ board ranks sellers by their monthly injection price. The table above prices each form on its own, so an injection is not averaged with a spray.
What a supplement is
Many NAD products on a store shelf hold a precursor, not NAD+. Nicotinamide riboside (NR) is one; the trial below calls it an NAD+ precursor vitamin[1]. Nicotinamide mononucleotide (NMN) is another.
NMN’s status changed. FDA had said NMN was excluded from the supplement definition[2]. On September 29, 2025, FDA reversed that position[2].
FDA was also clear about limits. Accepting a filing is not a finding that the ingredient is safe[2].
What an injection is
Injectable NAD+ is a compounded drug, on prescription. NAD is in FDA’s 503A Category 1[3]. That list holds substances under evaluation[3].
So both routes skip FDA approval. They skip it in different ways. The supplement is sold under supplement rules. The injection is compounded for one patient.
How injections, IV drips and sprays are priced is set out in the NAD+ price units guide. For clinic drips, see NAD IV therapy near me.
What the evidence says about raising NAD+
One randomized, placebo-controlled crossover trial tested NR in healthy middle-aged and older adults[1]. It ran two 6-week periods[1].
NR was well tolerated[1]. It elevated NAD+[1]. The authors called effects on blood pressure a question for future trials[1].
That is a measure of NAD+ levels. It is not proof of a health benefit. No trial cited here compares an injection with an oral precursor.
Who pays
IRS rules exclude most supplements from medical expenses[4]. The exception is a supplement a practitioner recommends to treat a diagnosed condition[4].
Prescribed drugs count[4]. Whether an account pays for a given prescription is covered in the HSA and FSA guide.
Whether insurance pays for an NAD drip is covered in does insurance cover NAD IV therapy.